Copper(I)-Catalyzed Multicomponent Reaction Providing a New Access to Fully Substituted Thiophene Derivatives

نویسندگان

  • Bo Jiang
  • Xing-Jun Tu
  • Xue Wang
  • Shu-Jiang Tu
  • Guigen Li
چکیده

Readily available triethylammonium 1-(2-oxoindolin-3-ylidene)-2-aroylethanethiolates are efficiently converted into a variety of fully substituted thiophene derivatives by copper(I)-catalyzed denitrogenative reactions with terminal alkynes and N-sulfonyl azides. This new reaction simultaneously installs C-N, C-S, and C-C bonds, allowing direct formation of highly functionalized thiophenes with a wide diversity in substituents in a one-pot manner. A plausible mechanism for the domino process is proposed.

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عنوان ژورنال:

دوره 16  شماره 

صفحات  -

تاریخ انتشار 2014